Calendula: A Natural Healer with Anti-Inflammatory Properties

Calendula: A Natural Healer with Anti-Inflammatory Properties

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Calendula, also known as marigold (Calendula officinalis), is a herbaceous plant widely recognized for its medicinal properties. Traditionally used for its healing abilities, modern science has begun to unveil the scientific basis for its effectiveness, particularly its anti-inflammatory and wound-healing properties. This article explores the evidence behind Calendula's health benefits.

1. Calendula: An Overview

Calendula is known for its vibrant orange or yellow flowers and is a staple in herbal medicine. Native to the Mediterranean region, it has been used for centuries in healing salves and tinctures.

2. Anti-Inflammatory Properties

One of the most significant benefits of Calendula is its ability to reduce inflammation.

  • Mechanism of Action: According to a study published in the "Journal of Wound Care," Calendula exhibits anti-inflammatory effects by inhibiting pro-inflammatory cytokines and promoting wound healing【1】.
  • Application in Skin Conditions: Its anti-inflammatory properties make it beneficial in treating various skin conditions, such as eczema and dermatitis.

3. Wound Healing Abilities

Calendula is widely used in topical applications for its wound healing abilities.

  • Promoting Tissue Repair: Research in the "Journal of Ethnopharmacology" has shown that Calendula stimulates tissue regeneration and granulation, essential for effective wound healing【2】.
  • Use in Post-Surgical Healing: Its ability to accelerate wound closure and reduce scarring makes it useful in post-surgical care, as noted in studies focusing on cesarean section and perineal tears.

4. Antimicrobial Effects

Calendula also possesses antimicrobial properties, enhancing its effectiveness in wound care.

  • Fighting Infection: The "Journal of Basic Microbiology" reports that Calendula extracts have antimicrobial activities against various bacteria, fungi, and viruses, preventing wound infections【3】.

5. Oral Health Applications

Besides its skin benefits, Calendula is beneficial in oral health.

  • Treatment of Oral Inflammation: Its anti-inflammatory properties are effective in treating gingivitis and other forms of oral inflammation. A study in the "International Journal of Dental Hygiene" found Calendula effective in reducing dental plaque and gingival inflammation【4】.

6. Calendula in Oncology

Emerging research suggests Calendula's potential in oncology, particularly in managing radiation-induced skin damage.

  • Radiation Dermatitis: A study in the "Journal of Clinical Oncology" found that topical application of Calendula reduced the incidence of grade 2 or higher acute dermatitis during radiation therapy for breast cancer【5】.

7. Safety and Dosage

Calendula is generally safe when used appropriately.

  • Recommended Dosage: While there is no standard dosage, it is important to follow product-specific recommendations or consult with a healthcare provider.
  • Side Effects: Calendula is well-tolerated, but allergic reactions may occur, especially in individuals sensitive to the Asteraceae/Compositae family.

8. Incorporating Calendula into Your Routine

Calendula can be used in various forms, including creams, ointments, tinctures, and teas. It's important to choose high-quality products to ensure efficacy.


Calendula is a versatile herb with significant anti-inflammatory and wound-healing properties. Its use in skin care, oral health, and even in oncological contexts highlights its broad therapeutic potential. As with any herbal remedy, considering individual health circumstances and consulting with a healthcare provider is advisable.


  1. Preethi K.C., Kuttan R. (2009). "Wound healing activity of flower extract of Calendula officinalis." Journal of Wound Care.
  2. Parente L.M., Lino Júnior R.S., Tresvenzol L.M.F., et al. (2012). "Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil." Journal of Ethnopharmacology.
  3. Efstratiou E., Hussain A.I., Nigam P.S., et al. (2012). "Antimicrobial activity of Calendula officinalis petal extracts against fungi, as well as Gram-negative and Gram-positive clinical pathogens." Journal of Basic Microbiology.
  4. Mahboubi M. (2019). "Calendula officinalis as a medicinal plant and its applications in dentistry." International Journal of Dental Hygiene.
  5. Pommier P., Gomez F., Sunyach M.P., et al. (2004). "Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer." Journal of Clinical Oncology.


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